5 Amazing Benefits of Doing a Metabolic Detox

by Dr. Nick Zyrowski August 31, 2021

Our modern diets and lifestyles put the human body at risk. Stress and poor nutrition can lead to poor health and wellness. A metabolic detox can help remove inflammation and improve overall physical and mental health.

Before we cover the many benefits of a metabolic detox, let's discuss what a metabolic detox is and how to do one.

What Is a Metabolic Detox? 

Metabolic detoxification is the process by which unwanted chemicals are eliminated from the body. For example, to destroy them, the body will metabolize xenobiotics and unwanted antibiotics.

The same enzyme detoxification systems can remove excess hormones, toxic substances such as heavy metals and chemical substances from preservatives and pesticides. Therefore, metabolic detoxification is essential for maintaining internal equilibrium and protecting the body against environmental factors.

B vitamins and sulforaphane are natural interventions that can support detoxification pathways by encouraging the activity of essential enzymes. Although herbs like silymarin often help in improving metabolism, carrying out a complete metabolic detox is more complicated than a dietary recommendation, and needs more elaborate research and analysis.

Not to be confused with the body's ability to detoxify itself. The best way to detox is to provide your body with the essential vitamins, minerals, and other nutrients. Unfortunately, many diets and trend claims to detox the body go against scientific logic and prove harmful.

How Is a Metabolic Detox Done?

Metabolic detoxification refers to eliminating toxins using a complex integrated system that converts lipid-soluble toxins into water-soluble molecules. These molecules will then be excreted directly by the body. One can do it in three phases.

Phase i

Phase 1 is about removing toxins from their storage locations. Phase 1 is about removing toxic substances from storage sites. Toxins can be found in fat cells, bones marrow, muscles, blood, liver, and the central nervous system. It is a way to unlock toxins and make them more water-soluble.

Different enzymes catalyze Phase 1 reactions, mainly from the Cytochrome P450 (CYP450 family) enzymes. The toxins become active again and can be more harmful if they aren't correctly by Phase 2 or Phase 3.

To minimize the adverse effects, it is vital to ensure no significant deficiencies before beginning Phase 1. Make sure gut function is assessed; look for vitamin D, magnesium, and B12 deficiencies as a starting point. In addition, a methylation profile test should be performed in cases where there is a possibility of an endogenous toxic burden.

Phase ii

Phase 2 is the conjugation of toxic substances. This is the phase where toxins, like free radicals, are neutralized and can be removed.

A protein called nuclear factor-erythroid-2 (NrF2) controls the production of most Phase 2 enzymes. This is where the primary role of conjugation enzymes are made from amino acids plays a key role. Glycine and glutamate are the two most important. These should be included in the detoxification program, as well as the diet during and after detoxification.

Plant phytonutrients may increase NrF2 to support Phase 2 and modulate endogenous antioxidants. Many plants support this pathway, but the Spanish black radish is the most important. For metabolic detoxification, milk thistle should also be used to protect the liver and prevent glutathione depletion.

Phase iii

In Phase 3, all toxins are eliminated through the kidneys and bowels. Again, fiber aids toxin removal while soluble dietary fibers aid urinary excretion. In addition, fiber is a prebiotic that helps produce beneficial bacteria within the gastrointestinal (GI) tract. This improves overall GI health. The bottom line is that if they aren't appropriately eliminated, toxic substances will be released into the bloodstream and processed again by the liver. They may be stored furthermore, making them even more harmful. A proper metabolic detoxification program can support this.

Patients shouldn't feel that this requires them to know every bathroom within a five-mile radius. However, patients must have regular bowel movements and drink enough water to support their kidney and bowel health.

What to Expect When Doing a Metabolic Detox 

Some people experience mild symptoms when they go through a metabolic detoxification program. These are commonly known as detox reactions, especially during the first detox. These symptoms can occur when detoxification processes are unbalanced or metabolic toxins are not properly eliminated. This is called a biological bottleneck problem, where the body's ability to transport and eliminate toxins exceeds its capacity. However, most symptoms are minor and disappear within a few days.

1. Headaches, Irritability, and Tiredness

You may experience withdrawal symptoms such as tiredness, headaches, and irritability when you suddenly stop drinking caffeine, sugar, and wheat.


  • Green tea, low in caffeine, has a hydrating effect and provides the body with L theanine. This supports the production of calming neurotransmitters.
  • Hydration should be increased.
  • Encourage an alkaline state with Nutritional Support through foods like vegetables, fruits, or herbs.
  • High-quality protein, fiber, fat, and other nutrients are essential to stabilize blood sugar.
  • Maximize your sleep quality and quantity
  • Encourage sweating in a sauna or steam room.
  • Eat clean foods to promote good bowel health

2. Food Cravings

Our diet is a major source of toxin exposure. People often experience cravings for food while following an elimination diet. In a few days, cravings will disappear. However, there are many reasons why you might feel hungry during detoxification programs.

  • Reduction of addictive foods and drinks
  • Sugar habits are broken.
  • Dietary changes can cause microbial imbalances in the digestive system.

Sugar, gluten, and dairy trigger an opioid-like response within the brain. This can lead to an addiction to sweet flavors. Food cravings can also be affected by the state of the microbiome. Certain strains are known to trigger cravings. Even though the microbes in the gut can cause cravings, they may be to the disadvantage of the host. These microbes can also cause the host to feel sick until they are satisfied. Then a feeling of euphoria sets in.4 Metabolic detoxification and its dietary components can help shift the microbiome to address dysbiosis. Another benefit is the ability to conquer sugar cravings and other unhealthy food cravings.


  • Increase the intake of alkaline foods, beverages, and other nutrients in your diet to help reduce food cravings and promote positive shifts in gut microbes.
  • Increase protein intake and eat more fruits and vegetables to avoid sugar cravings
  • Roast sweet potatoes or parsnip wedges for starchy food cravings or fried food

There are often suitable substitutes for cravings that work within the plan. A nutrition professional can help you manage and redirect food cravings, leading to lasting diet changes.

3. Bowel Irregularity

Constipation is the enemy of detox. Many toxins can be eliminated through the stool. Although detoxification meal plans often include nutritional support and a high-fiber diet, many people experience digestive symptoms such as bowel irregularities or bowel problems.


  • Get plenty of water, herbal teas, and other fluids
  • You can eat bitter vegetables and herbs such as endive, radicchio, and ginger to promote healthy peristalsis
  • Take a magnesium dietary supplement
  • High-fiber vegetables and healthy fats, oils, and seeds that are not starchy help to lubricate your digestive tract
  • Regular exercise is an excellent way to increase your fitness

These solutions can help both consumers and professionals feel more confident about participating in metabolic detoxification programs. In addition, people can reap the benefits from periodic metabolic detoxification programs by understanding why they experience symptoms and how to deal with them.

The 5 Primary Benefits of a Metabolic Detox 

1. Energy levels increase

The body's inability to absorb, process, and use nutrients from food can lead to fatigue, sluggishness, and lack of energy. In addition, the body can experience a decrease in energy if toxins are accumulated. A detoxification program that includes proper nutrition can jump-start digestion and increase energy production at the cellular level. As a result, you will feel more energetic and lighter after this period of cleansing. You may even experience an easier time with weight loss due to the extra energy.

2. Mental clarity improves

Because the brain and gut are connected, any problem in the stomach can also affect the brain. Brain fog is caused by a high level of toxins in the brain. This can cause brain fog and slow down information processing. A period of detoxification gives the brain an energy boost that improves focus and mental clarity. A full body detox can lead to neurological benefits. Different toxins can dissolve in fat so that one may feel adverse effects on the brain immediately. This is due to the large amount of fat found in the brain. A well-planned, complete body detox can help to clear the path for neurological benefits.

3. Liver function improves

The liver is the main detoxification organ that works tirelessly to remove harmful substances and pollutants from the body. The liver can also benefit from a detox/cleanse, which is essentially a break from its constant work. The detox is designed to help the liver function at its best to perform essential metabolic and detoxification processes.

4. Immune system strengthens

Toxin accumulation can affect all bodily functions, including the immune and lymphatic systems. A lower immunity indicates a greater susceptibility to infection and disease. Complete body cleansing is recommended for those with poor immune health. A detox period improves the immune system's function, and white blood cells can work more effectively to fight foreign bodies and microorganisms.

5. Skin becomes clean and healthy

The skin is a primary detoxification organ, and any imbalance or toxin accumulation in the body shows through the skin. However, with a metabolic detox, your skin will experience rejuvenation.

How a Metabolic Detox Differs From Other Detoxes

A metabolic detox program offers a long-term solution, and it requires dietary and lifestyle changes. The metabolic toxins from metabolic detox are removed through the liver, while many other detoxes are removed through the digestive tract. 

For another alternative, be sure to check out our 90-day True Cellular Detox kit.

A Metabolic Detox and Your Health

A metabolic detox helps to get rid of harmful toxins from your body, its benefits are as extensive for your health as they are straightforward and understandable. Such a detox cleanses your physiology as well as provides psychological benefits, reinvigorating your mental state alongside your physical health. Get a metabolic detox done today to improve the quality of your lifestyle. 

Please consult your doctor or healthcare professional before using any kind of supplement.

Dr. Nick Zyrowski
Dr. Nick Zyrowski