Colon Cancer Is on the Rise: How Much, Why It’s Happening, and the Hidden Role of GMOs & Pesticides

by Dr. Nick Zyrowski December 08, 2025

Colon cancer is no longer a disease that primarily affects older adults. In fact, it’s becoming alarmingly common in people under 50—and the trend is accelerating. Researchers have been sounding the alarm for years, but new data reveals just how serious the problem has become.

According to the American Cancer Society, colon cancer rates among younger adults have been increasing by 1–2% per year, and cases in the 20–39 age group have jumped significantly over the last two decades. Even more concerning, younger patients often present with more aggressive disease.

So what’s driving this rise?

Genetics only explain a small fraction of colon cancer cases. That means environmental exposures, diet, toxins, and modern agricultural practices are likely much bigger players than we once believed. And among the most concerning suspects: GMO foods and the pervasive use of pesticides like glyphosate.

Let’s break down what’s really going on—and what you can do to protect yourself and your family.


Colon Cancer Is Increasing—Especially in Younger Adults

Colon cancer rates among adults under 50 have been steadily rising. In fact:

  • Early-onset colorectal cancer has more than doubled since the 1990s.
  • The American Cancer Society reports a 1–2% increase every year in colorectal cancer among younger adults.
  • Colon cancer is now a leading cause of cancer death in men and women under 50.

 This trend is not random. It’s happening too quickly to be driven by genetic changes alone. That means environmental, nutritional, and lifestyle factors are the real drivers—factors we can influence.


Why the Spike? Look Beyond Genetics

Only about 5–10% of colon cancer cases are genetically inherited. That means the other 90–95% stem from environmental inputs that create chronic inflammation, disrupt the microbiome, damage DNA, and impair detox pathways.

Two major contributors that have gained attention are:

1. GMO Foods 

Genetically modified crops—particularly soy, corn, sugar beets, canola, and cottonseed—are widely consumed in the U.S. These crops are commonly engineered to tolerate heavy pesticide use, especially glyphosate. The concern isn’t only about the genetic modification itself, but also the chemical load that comes with it. 

GMOs have been linked to: 

  • Disruption of the gut microbiome
  • Increased intestinal permeability (“leaky gut”)
  • Higher glyphosate residues in the body 
  • Chronic low-grade inflammation 

All of these factors create an environment in the gut that is more vulnerable to precancerous changes.

2. Pesticides & Herbicides (Including Glyphosate)

Glyphosate is the most widely used herbicide in the world—and residue testing shows it’s now present in the majority of popular U.S. foods. This is especially concerning because the gut is the first point of contact.

Glyphosate exposure has been associated with:

  • Microbiome imbalance (killing beneficial bacteria)
  • Mitochondrial dysfunction
  • Oxidative stress
  • Impaired detoxification
  • Hormone disruption 

These biological stressors contribute to cellular inflammation and DNA damage, both of which increase cancer risk—especially in the colon, where these chemicals accumulate.


Where Are These Chemicals Hiding? 

Every year, the Environmental Working Group (EWG) releases the Dirty Dozen—a list of the top 12 fruits and vegetables with the highest pesticide residues.

 For 2025, items commonly appearing on the list include:

  • Strawberries
  • Spinach
  • Kale, collards, and mustard greens
  • Apples
  • Grapes
  • Peaches
  • Pears
  • Bell peppers
  • Cherries
  • Blueberries 

These are foods most people assume are healthy—but when grown conventionally, they often carry multiple pesticide residues per sample.

Choosing organic for these items can significantly reduce your toxic burden.


How Pesticides Harm the Gut (and Why That Matters for Colon Cancer)

The gut is ground zero when it comes to exposure to pesticides and GMO contaminants. Research shows these chemicals can:

1. Damage the Gut Lining 

Glyphosate weakens tight junctions in the intestinal wall, increasing intestinal permeability ("leaky gut"). A compromised gut barrier increases systemic inflammation—one of the major drivers of cancer.

2. Disrupt the Microbiome

Glyphosate acts as an antibiotic, wiping out beneficial bacteria that protect the colon and support immune health.

3. Increase Oxidative Stress

This accelerates cellular damage and aging of the colon wall.

4. Interfere With Detoxification Pathways

The more toxic the gut becomes, the harder it is for the liver and immune system to keep up.

All of this creates an environment where cancerous changes can take root. 


What You Can Do: Practical Steps to Protect Colon Health

1. Prioritize Organic Choices (Especially the Dirty Dozen) 

You don’t have to buy everything organic, but the “Dirty Dozen” list is a smart place to start. These are the crops with the highest pesticide loads.

2. Reduce Processed Foods

Most processed foods contain GMO corn, soy, canola oil, and sugar beets—often hidden in:

  • Chips
  • Cereal
  • Snack bars
  • Salad dressings
  • Baked goods
  • Restaurant meals 

Cutting back significantly reduces pesticide exposure and inflammation.

3. Support Detox Pathways

Your body is designed to detoxify environmental chemicals—but it needs the proper nutrients. Focus on:

  • Cruciferous vegetables
  • Clean water
  • Sweating regularly
  • Liver-support nutrients (sulfur-rich foods, NAC, milk thistle)

 If someone has a history of toxic exposure or digestive issues, a structured cellular detox program can be extremely helpful in restoring proper function.

4. Heal and Strengthen the Gut

A healthy gut is one of your strongest defenses against colon cancer. When the intestinal lining is strong and the microbiome is balanced, inflammation decreases, toxins are better managed, and immune surveillance improves.

Supporting the gut requires more than probiotics and enzymes alone. While those play important roles, the gut lining itself often needs targeted nourishment to repair and strengthen. That’s where GI Repair by Celarity becomes extremely valuable.

GI Repair provides a comprehensive blend of nutrients specifically designed to support gut lining integrity and reduce inflammation, including:

  • Glutamine – the primary fuel source for intestinal cells, essential for repairing the gut barrier
  • Licorice root extract – helps calm irritation and support mucosal defenses
  • Arabinogalactan – promotes beneficial bacteria and supports immune balance in the gut
  • Aloe leaf extract – soothes the GI tract and supports tissue healing 

When healing the gastrointestinal system, targeted nutrients like these are essential for:

  • Balancing gut bacteria
  • Dampening inflammation
  • Calming the immune response
  • Strengthening the protective mucosal barrier 

Together, this creates a healthier internal environment—one that’s more resilient and less prone to chronic irritation or cellular changes that increase colon cancer risk.

5. Reduce Glyphosate Exposure

Some practical tips:

  • Choose organic grains when possible
  • Filter tap water
  • Avoid produce on the
  • Dirty Dozen list if not organic
  • Eat more home-cooked meals and fewer packaged foods 

Even small changes dramatically reduce your cumulative exposure.

6. Live a Low-Inflammation Lifestyle

Constant inflammation is fuel for cancer. Reduce it by:

  • Prioritizing sleep
  • Managing stress
  • Exercising regularly
  • Avoiding smoking and excessive alcohol
  • Eating an anti-inflammatory diet 

Your colon—and your whole body—will thank you.


Final Thoughts: Environment Matters More Than Genetics

The rapid rise in colon cancer—especially in younger adults—can’t be blamed on genes. The environment we live in and the food we eat are changing faster than our DNA ever could.

The good news?

You have the ability to change your internal environment starting today. By lowering toxic exposures, supporting detoxification, healing the gut, and prioritizing real food, you reduce your risk significantly and strengthen your long-term health.

Dr. Nick Zyrowski
Dr. Nick Zyrowski