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Vascular Support NO delivers an extended-release nitric oxide precursor. Scientists now refer to nitric oxide (NO) as the “foundation” of cardiovascular health. This tiny molecule is a vasodilator responsible for controlling blood flow to the entire body, which may help support healthy blood flow pressure and promote the health of the endothelium—the inside of blood vessels. With age comes diminished NO levels; that’s why since 1998, when 3 scientists won the Nobel Prize for their discovery of NO, researchers have been working to harness its heart-healthy activity. Today, with the application of Celarity's extended-release technology, that activity has been realized with Vascular Support NO.
If you have high blood pressure issues, you want the best cardiovascular supplement, free of fillers and additives. That’s why we’re offering Vascular Support NO, a non-GMO, 3rd party tested blood pressure support supplement to keep your heart healthy.
High blood pressure is a health concern that is growing at an alarming rate. The Center for Disease Control and Prevention reports that 1 in 3 Americans are suffering from high blood pressure. This equates to about 70 million people. Of this 70 million, it is estimated that half of the people have uncontrolled blood pressure, putting you at serious risk for major health problems like:
Vascular Health (along with high blood pressure) has become a passionate subject for me as I see so many of my own family members, friends and patients struggle to manage and maintain healthy blood pressure levels. Time and time again, I see these people put on high blood pressure medication with no plan of coming off of them.
There are many strategies that can be used in the holistic realm in order to support healthy blood pressure levels and vascular health. The good news is that they can be used without all the side effects. With Vascular Support NO's synergistic blend of scientifically proven ingredients, we now have a strategy backed by science to offer individuals the support they need.
Vascular Support NO elevates the plasma level of L-arginine, a “semi-essential” amino acid and important nutrient whose remarkable properties are validated by a Nobel Prize in medicine (1998). More than 60,000 clinical studies have brought L-arginine to the forefront of modern medicine as a nutrient that offers a wide range of health benefits. Vascular Support NO provides L-arginine in extended-release form to prolong its bioavailability.
L-arginine is considered a direct nitric oxide (NO) precursor as it is the substrate of nitric oxide-generating enzymes called nitric oxide synthetases (NOS). Nitric oxide is an endogenously produced cellular signaling molecule involved in a variety of endothelium-mediated actions in the vasculature.1The plasma concentration of L-arginine might be a rate-limiting factor for NO production. Research in humans suggests that oral supplementation with L-arginine may increase smooth muscle relaxation, inhibit platelet aggregation, and inhibit expression of adhesion molecules and endolelin-1.2L-arginine drives the biosynthesis of NO in tissues, including the vascular endothelium and skeletal muscle.3Acting via the cyclic guanosine monophosphate (cGMP) intracellular signaling system, NO increases blood flow without increasing blood pressure.4In short, NO causes vasodilation by inhibiting smooth muscle contraction. Increased blood flow results in increased nutrient uptake and glucose utilization in muscle, especially during exercise.4
In addition to the cardiovascular/circulatory benefits, L-arginine is involved in ammonia detoxification, hormone secretion, and immune health. It supports the synthesis of protein as well.5The generation of nitric oxide may act as a molecular switch that activates PGC-1α, the master regulator of mitochondrial biogenesis and energy metabolism.6Many athletes have safely and effectively used L-arginine to increase “muscle pump” during a workout and for several hours afterward. Additional desired benefits include an increase in overall workout capacity (muscular endurance) and an increase in post-exercise recovery.7
ACTINOS™is a mixture of both high- and low-molecular weight fractions of proteins and peptides derived from whey. Research suggests that these fractions are NOS activators that boost NO production by factors unrelated to arginine, calcium, or bradykinin. ACTINOS may enhance transcription of the NOS gene and supports its role in reducing the negative feedback mechanism for NO production. The synergistic activity of the size-based fractions of ACTINOS has been shown to increase NO production in human endothelial cells in vitro from 9.5 to 12.7 times compared to a control.8
Vascular Support NO is manufactured in the United States using the highest purity (>98.0%) of L-arginine alpha-Ketoglutarate that is commercially available. This formulation is specially designed to deliver L-arginine alpha-Ketoglutarate in a controlled manner over a period of approximately 4-6 hours.
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Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
