Neurotransmitters are the brain chemicals that facilitate the transmission of signals from one neuron to the next across a synapse. Neurotransmitters work with receptors in the brain to influence and regulate a wide range of processes such as mental performance, emotions, pain response and energy levels. Functioning primarily in the Central Nervous System (CNS), neurotransmitters are the brain’s chemical messengers, facilitating communication among the body’s glands, organs, and muscles. Numerous clinical studies have shown that inadequate neurotransmitter function has a profound influence on overall health and well-being. In fact, imbalances in certain neurotransmitters are associated with most of the prevalent symptoms and conditions seen in practitioners offices today.
- Mood disorders; depression, anxiety
- Adrenal dysfunction; fatigue, insomnia
- Loss of mental focus; ADD, ADHD, cognitive fog
- Addiction and dependency
- Hormonal imbalances; E2 dominance, E2 deficiency, low androgens
- Loss of appetite control; insulin resistance
Compounding these symptoms of imbalance are the myriad of bioactive substances like caffeine, alcohol and nicotine and many of the medications used to manage these conditions as well as some cholesterol lowering medications. These substances and medications can contribute to neurotransmitter depletion and resulting symptoms by suppressing or artificially stimulating neurotransmitter receptor function. When functioning properly the neurotransmission system has natural checks and balances in the form of excitatory and inhibitory neurotransmitters. These are classified according to their effects on postsynaptic membranes (receptor sites). Excitatory neurotransmitters cause depolarization of the membrane and promote an action potential. Inhibitory neurotransmitters cause hyperpolarization and depresses or inhibit an action potential.
Putting It All Together
Identifying and managing neurotransmitter imbalances is facilitated with a noninvasive urinary test. Testing provides a tool to understand each patient’s specific neuroendocrine imbalances, which can be corrected with nutraceuticals, BHRT, diet, and lifestyle interventions. Information on this website identifies numerous symptoms and conditions associated with neurotransmitter imbalances. It is especially important to understand that there are agonistic/antagonistic interrelationships of the neurotransmitters with adrenal hormones and sex hormones. Changes in sex hormones and adrenal hormones can lead to neurotransmitter imbalances. And at the same time, neurotransmitter imbalances will affect hormone production and function. Testing both neurotransmitters and hormones provides a comprehensive view of the body’s functional neuroendocrine status, and brings to light additional factors that may be contributing to symptoms.
Who Should Be Tested
Neurotransmitters are powerful chemicals that regulate numerous physical and emotional processes such as mental performance, emotional state, physical energy, and pain response. Imbalances in certain neurotransmitters are associated with most of the prevalent symptoms and conditions seen in practitioners offices today. Neurotransmitter testing may be applicable to both male and female patients. Expression of the following symptoms can indicate neurotransmitter imbalances:
- Depressed mood
- Adrenal dysfunction
- Poor sleep
- Loss of mental focus, or cognitive fog
- ADD and ADHD
- Addiction or dependency
- Loss of appetite control
- Compulsive behavior
- Low libido
- Sexual dysfunction
Adrenal hormones, sex hormones, and neurotransmitters are functionally interrelated. Changes in sex hormones and adrenal hormones can lead to neurotransmitter imbalances. In turn, neurotransmitter imbalances can affect hormone function. Including neurotransmitters with hormone panels provides a more comprehensive view of the body’s functional neuroendocrine status, this interrelationship, and the associated factors that may be contributing to symptoms.
Specimen Type: Urine
NOTE: This lab is not currently available in New York, Rhode Island, New Jersey or if you live outside of the United States. If you live in one of these regions, we cannot order labs. However, we can partner with you and give you physician level advice and coaching to optimize your health. If you would like to schedule an appointment, please contact our office by calling 586-703-0228.