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Many health problems are caused when bacteria and yeast overgrowth is present in the GI tract. When this is the case, it’s crucial to remove the bad bacteria from your gut, and put the right kind of bacteria back in your system. Microbe Cleanse by Celarity helps to establish a healthy microbiome balance in your GI tract, while also getting rid of candida using powerful nutrients like berberine and Oregon grape root. This effective gut healing formula is a key component included in the SIBO kit and used with other regimens that work to balance and restore your gut microflora.
Celarity’s Microbe Cleanse combines a blend of herbs, essential oils, and sodium caprylate, a naturally occurring fatty acid, to give you the most effective product to restore healthy gut microflora. This extensive formula is designed to address gastrointestinal distress caused by pathogen imbalance, immune dysfunction, and inflammatory gastrointestinal conditions. All of these circumstances have a direct impact on your overall health and wellness when gastrointestinal conditions emerge. This is a highly developed approach based on key nutrition research for the best results.
APPLICATIONS
COMMON SYMPTOMS OF BACTERIAL AND YEAST OVERGROWTH
INGREDIENTS THAT WORK
Plants have been used for thousands of years for their medicinal properties. Many pharmaceutical drugs are derived from plants. Microbe Cleanse includes a complementary blend of ingredients specifically formulated to support microbial balance, antioxidant activity, and gastrointestinal function. These are provided in easy-dissolving vegetarian capsules that do not contain wheat, gluten, yeast, soy, animal, or dairy products. They are also free of fish, shellfish, nuts, eggs, GMOs, or artificial preservatives of any kind.
BERBERINE
Berberine is a benzylisoquinoline alkaloid that has been widely used in Chinese medicine for centuries. Studies suggest berberine can be highly beneficial for a variety of therapeutic applications, including gastrointestinal health and microbial balance.
Randomized controlled trials from the 1960s and 1980s have established evidence to support berberine’s effectiveness for loose stools. It has been used as an anti-diarrhea agent, especially when certain bacteria strains are present.
Increased evidence has indicated that gut microbiota is crucial to regulate the pharmacokinetic and biological effects of berberine. When berberine is exposed to specific bacterial, fungal, and viral strains, it has been shown to inhibit microbial synthesis. Berberine also regulates gut microbe-dependent metabolites, which contribute to its biological effects on lipid and glucose metabolism. Gut microbiota also influences the bioavailability of berberine and is required for its conversion to the intestine-absorbable form.
Microbe Cleanse contains 250 mg of berberine per dose. It is complemented by Oregon grape root, GSE, and uva ursi extract. This multidimensional formula is designed to provide support for healthy microbial activity while also promoting GI health.
OREGON GRAPE ROOT
Oregon Grape Root contains a range of isoquinoline alkaloids, including berberine. Once known as Indian barberry, Oregon grape was traditionally used by North American tribal communities for liver, gall bladder, kidney, and GI ailments as well as for a general health tonic. Studies support its antimicrobial qualities, its use in regulating bile acid metabolism, and its contribution to epithelial regeneration by increasing mucosal secretions, which are critical for GI microflora proliferation, intestinal absorption, and intestinal motility.[8]
GRAPEFRUIT SEED EXTRACT
Grapefruit Seed Extract (GSE) contains polyphenols that are converted into a diverse class of quaternary ammonium compounds and used by the food processing and agricultural industries for their antimicrobial effect. Additionally, GSE is used as a natural remedy for GI issues linked to microbial imbalance, but it has been hypothesized that this clinically observed benefit may be attributable to the preservatives in the extract.*[9]
In vitro research has shown that GSE has an inhibitory effect on various bacterial biotypes, yeasts, and molds.[10,11] In vivo research is limited, but a small trial in patients (n = 15) with atopic eczema was designed to assess the effect of GSE extract on several bacterial and yeast strains. It demonstrated that oral administration of 150 mg of GSE three times per day resulted in varying degrees of inhibition of some fungal and bacterial species, and an improvement in GI symptoms was noted in all patients.[11] The above findings indicate antimicrobial potential for non-adulterated GSE; however, randomized, double-blind, placebo-controlled human trials with large subject groups are needed to further substantiate GSE for this use.*
UVA URSI (BEARBERRY LEAF)
Uva Ursi is a traditionally used remedy for urinary tract infections. The constituent in uva ursi that appears to have an antimicrobial effect is the phenolic glycoside arbutin, which undergoes hepatic conjugation to form hydroquinone (HQ).[12] A review of published and unpublished human and experimental studies summarized the evidence relating to the safety and efficacy of uva ursi extract in supporting lower urinary tract health. Pharmacokinetic data suggest that the intake of 420 mg of HQ (calculated as anhydrous arbutin) is a safe, therapeutic option.*[13]
WHY DR. ZYROWSKI USES MICROBE CLEANSE
This formula is an essential piece of clearing out pathogens and yeast from the intestines. Many conditions have excess bacteria and yeast overgrowth in the GI tract. Not only is it important to support the gut with proper nutrients and good bacteria, but it is crucial to remove the bad bacteria and yeast. This is where Microbe Cleanse shines and why I use this as one of the most important supplements for bacteria and yeast overgrowth.
Celarity Company Statement
Celarity Microbe Cleanse is a state of the art product that is pharmaceutical grade and only to be sold by licensed practitioners. Celarity prides itself on being on the forefront of innovation in the natural health and holistic healing field. Celarity also prides itself on working with innovative doctors who are disruptors in the health care field.
Count: 60 vegetarian capsules
Suggested use: Take one to two capsules, once daily, or as directed by your healthcare practitioner.
Does not contain: Wheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
References:
1. Gaba S, Saini A, Singh G, et al. Bioorg Med Chem. 2021;38:116143. doi:10.1016/j.bmc.2021.116143
2. Sack RB, Froehlich JL. Infect Immun. 1982;35(2):471-475. doi:10.1128/iai.35.2.471-475.1982
3. Amin AH, Subbaiah TV, Abbasi KM. Can J Microbiol. 1969;15(9):1067-1076. doi:10.1139/ m69-190
4. Wolf PG, Devendran S, Doden HL, et al. BMC Microbiol. 2021;21(1):24. doi:10.1186/s12866-020-02020-1
5. Rabbani GH, Butler T, Knight J, et al. J Infect Dis. 1987;155(5):979-984. doi:10.1093/infdis/155.5.979
6. Yang S, Li D, Yu Z, et al. Front Pharmacol. 2021;12:709629. doi:10.3389/fphar.2021.709629
7. Feng R, Shou JW, Zhao ZX, et al. Sci Rep. 2015;5:12155. doi:10.1038/srep12155
8. Davis R. Oregon Grape (Berberis spp.). Accessed May 25, 2022. https://www.herbrally.com/monographs/oregon-grape
9. Grapefruit. In: Natural Medicines – Professional. Therapeutic Research Center. Updated November 10, 2021. Accessed February 8, 2022. https://naturalmedicines.therapeuticresearch. com/databases/food,-herbs-supplements/professional.aspx?productid=946
10. Reagor L, Gusman J, McCoy L, et al. J Altern Complement Med. 2002;8(3):325-332.doi:10.1089/10755530260128014
11. Ionescu G, Kiehl R, Wichmann-Kunz F, et al. J Orthomol Med. 1990;5(3):155-157.
12. Head KA. Altern Med Rev. 2008;13(3):227-244. 13. de Arriba SG, Naser B, Nolte KU. Int J Toxicol. 2013;32(6):442-453.doi:10.1177/1091581813507721
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
