The Science Behind NAD+: Your Fountain of Youth in the Modern Age

by Dr. Nick Zyrowski May 23, 2024

In all of our messages, we always tell you that true health only happens naturally. When it comes to wellness, you want the most efficient methods that give you the best results. Instead of going to health food stores and grabbing random bottles of supplements that may have no benefit, it’s crucial to use what works. In this article, we’ll uncover what you need to know about NAD+ and why it’s called a fountain of youth by many who use it.

What is NAD+?

NAD+ is an acronym for nicotinamide adenine dinucleotide. Let’s break that down so you can see exactly how NAD+ works for your body. First, it is a coenzyme that is essential for creating energy. It’s also included in numerous metabolic processes. (1)

Although you may have only recently heard of it, the molecule NAD+ is critical for your health and longevity. Since it plays so many roles in the body’s biological processes, like DNA repair, healthy metabolism, and gene expression, you can see why you need it. If this is a natural molecule, why do we need more of it?

As we age, it seems a decline in NAD+ may be inevitable. That may be due to inflammation, disease, stress, or other factors. Interventions to increase NAD+ are thought to possibly slow the aging process, making it the proverbial fountain of youth. (2) NAD+ works by slowing down the biological clock that affects most people.

How to increase NAD+

Supplementing is one of the best ways to increase NAD+, but there are other methods you can also use to naturally raise your levels.

Exercise: Regular exercise is an easy and effective way to boost NAD+, and you won’t need fancy equipment. Breaking a sweat with a brisk walk or lifting some free weights increases the demand for cellular energy, so your body will produce more NAD+ to support energy production. 

Eating healthy foods: To get more NAD+, you should eat foods rich in nutrients. Consume eggs, beef, avocados, salmon, and fermented foods that are high in vitamin B3, a precursor to NAD+.

Benefits of supplementing NAD+

If you want to be active once you approach your 40s and 50s, you may want to include NAD+ in your supplement stack. Many people believe you naturally slow down as you age, but that does not have to be the case. NAD+ supports the healthy aging process. (3)

NAD+ converts the food we eat into cellular energy, which cells rely on to perform vital functions throughout your body. It activates your longevity factors.

Since research shows our NAD+ levels decrease by about 50% every 20 years, and this decline is accelerated by our modern lifestyles. Therefore, using supplements to restore our levels may be necessary. (4)

Boosting NAD+ may improve cognitive function. As we age, some of our cognitive function declines. We may experience brain fog, memory loss, or even difficulty concentrating on daily tasks. These may all be attributed to insufficient levels of NAD+. If you don’t have enough, your brain may not convert glucose to energy, which means your brain’s cellular energy is depleted. ( 5)

Since research shows our NAD+ levels decrease by about 20 years, and this decline is accelerated by our modern lifestyles. Therefore, using supplements to restore our levels may be necessary. NAD+ also activates your longevity factors called sirtuins (SIRTs), via this interaction NAD+ can enhance your cellular health providing whole-body benefits. (6)

Boosting NAD+ may improve cognitive function. As we age, some of our cognitive function declines. We may experience brain fog, memory loss, or even difficulty concentrating on daily tasks. These may all be attributed to insufficient levels of NAD+. If you don’t have enough, your brain may not convert glucose to energy, which means your brain’s cellular energy is depleted.

Proper NAD+ levels may help you maintain a healthy weight. No, this is not a weight loss pill, but NAD+ is essential for metabolism. It makes sense that if your levels decline, you could pack on a few extra pounds that are difficult to get off.

NAD+ is also an energy booster. Again, this is where cellular energy comes into focus. NAD+ has been found to increase energy levels and decrease fatigue. (7) You may have heard people mention getting NAD+ infusions after being sick or when they have jet lag. It is incredibly effective for fighting off exhaustion., because NAD+ enhances mitochondrial function. Your mitochondria are your cells energy powerhouses producing your cellular energy. However, they become damaged and dysfunctional during aging contributing to mental and physical fatigue. NAD+ helps to repair damaged mitochondria and enhances their function.

A popular reason some people incorporate NAD+ into their supplement routine is because it reduces pain. That is because NAD+ decreases inflammation, and when you’re less inflamed, you naturally have less pain. 

If you want to elevate your mood, you could try NAD+ rather than getting dangerous pharmaceuticals. NAD+ has been shown to increase the feel-good hormone serotonin. Studies have shown a direct relationship between depression and anxiety and NAD+ levels. 

Addressing the NAD+ decline

Lately, the market has become flooded with NAD+ supplements. There are injections, IVs, NAD+ pills, and even precursor supplements. We often say that unless you get to the root cause of the problem, you’re only covering it up. Unfortunately, many NAD+ supplements on the market don’t address the root cause of NAD+ decline, so they are ineffective. (10)

Since you want an efficient AND effective method to increase NAD+ levels, you have to be picky when it comes to the supplements you use. Nuchido TIME+ is a next-generation supplement that supports cellular health. It’s a different product from others on the market because it is clinically proven to fix the root causes of NAD+ decline and restore youthful NAD+ production.

The main source of NAD+ in your cells is the Salvage Pathway, which continuously makes and recycles NAD+. When we are young the Salvage Pathway works very efficiently; however, its efficiency declines with age. Nuchido TIME+ reactivates the Salvage Pathway to restore your body's natural ability to produce NAD+.

Nuchido TIME+ also inhibits inflammatory molecules that waste large quantities of NAD+, so that the increased NAD+ can be directed towards beneficial pathways in your cells. (11)

[Use code DRNICK to save 10% on your first purchase of Nuchido TIME+]

https://nuchido.com/pages/choose-your-supply

In clinical trials with males and females from 20 to 80 years old, the results showed that Nuchido TIME+ increased cellular NAD+ levels within 7 days. It also restored the body’s natural NAD+ production pathway, reduced inflammation and glycation and reversed biological age. It also increased the longevity protein, SIRT1. (12)

Nuchido TIME+ includes a combination of ingredients that synergistically restore NAD+ production and have other health benefits, such as EGCG (green tea extract), alpha lipoic acid, and quercetin.

Customers who used Nuchido TIME+ reported improvements in mental and physical energy and sleep. They also had a reduction in brain fog.

Within one to three months, you may note improvements in your hair, skin, and nails. Other improvements may include enhanced mental clarity, faster recovery from exercise, and reduced menopause symptoms for women.

The Nutraceutical difference

You’ve likely heard of this term from “biohackers" who want to have an enhanced mental or physical edge. These products are being used by many people in the place of some pharmaceuticals. These substances are thought to have a physiological benefit or to protect the body against disease. 

Healthy nutraceuticals are changing the supplement industry. The focus is on disease prevention and sometimes reversing damage to the body.

Should you try NAD+?

Since we know NAD+ supports every cell in the body, we think most adults would benefit from increased levels. This is especially true as we age when NAD+ levels have been shown to dramatically decline.

If you’ve noticed that you don’t recover quite as quickly as you used to from a hard workout or want to reduce those brain fog symptoms, NAD+ could be an effective way to improve healthy bodily functions.

Remember, you don’t want to play a guessing game with your health. Too many people spend thousands of dollars on supplements that do no good. NAD+ is backed by scientific research and data to show how effective it can be in a short time. When looking for the right supplement, you want ingredients that restore your body’s natural NAD+ production. Nuchido TIME+ has been shown to increase cellular levels in just 7 days. And because I wanted to help make this an achievable goal for you, I locked in 10% off for my Wellness Warriors. 

Use code DRNICK to save 10% on your first purchase of Nuchido TIME+.

When it comes to your health, we want to help you become a wellness warrior. If you have questions about the best natural supplements or ways to improve your health, contact us for more information on how to get started today.

References

https://www.sciencedirect.com/science/article/pii/S0006295222000405?via%3Dihub

https://www.nature.com/articles/s41514-023-00134-0

https://conciergemdla.com/blog/difference-between-nad-nadh-and-nad - plus/#:~:text=Basically%2C%20NAD%2B%20is%20the%20biologically ,)%20%2B%20hydrogen %20(H).

https://www.nmn.com/precursors/what-is-nad

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495723/

https://www.bouncehydration.com/blog/benefits-of-nad-therapy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088772/#:~:text=Unfortunately%2C%20NAD%2 B%20levels%20steadily%20decline,of%20sirtuin%20and%20PARP%20activity.

https://www.elysiumhealth.com/blogs/aging101/what-is-nad-and-why-is-it- important#:~:text=NAD%2B%20is%20found%20in%20every,an%20endless%20supply%20of% 20NAD%2B.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346866/#:~:text=Apart%20from%20NA%2Dm ediated%20effects,of%20tissue%20inflammation%20%5B16%5D.

https://pubmed.ncbi.nlm.nih.gov/36118157/#:~:text=Linear%20trend%20analyses%20showed% 20a,%3D8.74E%2D5).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226615/#:~:text=These%20NAD%2B%20precu rsors%2C%20namely%20nicotinic,17%2C18%2C19%5D.

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.831168/full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336979/

https://www.news-medical.net/health/What-are-Nutraceuticals.aspx

https://nuchido.com/blogs/news/sirtuins-nad-and-aging

https://www.sciencedirect.com/science/article/pii/S0006295222000405?via%3Dihub

https://nuchido.com/blogs/news/how-is-nuchido-time-different-to-other-nad-products

https://www.nature.com/articles/s41514-023-00134-0

Dr. Nick Zyrowski
Dr. Nick Zyrowski